Luteal Phase Defect

When a suspected luteal phase defect occurs, the secretion of progesterone by the ovary is below normal or the endometrium isn’t responding to the normal stimulation of progesterone.

All Underlying Causes

About Luteal Phase Defect

A Luteal Phase Defect or LPD (because all things related to fertility lingo seems to have an acronym), is where there is an abnormality in the endometrial development. There is some debate surrounding luteal phase defect and its existence. When a suspected luteal phase defect occurs, the secretion of progesterone by the ovary is below normal or the endometrium isn’t responding to the normal stimulation of progesterone. A luteal phase defect are associated with both infertility and early miscarriage.

Most providers will diagnose luteal phase defect through conducting two, out-of-phase biopsies usually 2 days prior to the suspected start of menstruation.